Genzano di Roma to Niscemi trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Lanuvio and arrive at Niscemi every about 4 hours on average. If travelling with Trenitalia, you need to know the Genzano di Roma to Niscemi train schedule: the first train leaves at 06:00, while the last ride is at 21:17. A Genzano di Roma to Niscemi train cost about 79.85 €. But how long is the train ride from Genzano di Roma to Niscemi? Your journey takes about 16 hours on average.