Giussano to Castelvetrano trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Mariano Comense and arrive at Castelvetrano every about 2 hours on average. If travelling with Trenitalia, you need to know the Giussano to Castelvetrano train schedule: the first train leaves at 07:15, while the last ride is at 18:15. A Giussano to Castelvetrano train cost about 116.65 €. But how long is the train ride from Giussano to Castelvetrano? Your journey takes about 15 hours on average.