Giussano to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Mariano Comense, Salerno and arrive at Messina Centrale every about 1 hour on average. If travelling with Trenitalia, you need to know the Giussano to Messina train schedule: the first train leaves at 07:15, while the last ride is at 22:01. A Giussano to Messina train cost about 104.9 €. But how long is the train ride from Giussano to Messina? Your journey takes about 14 hours on average. If you need to travel this week, prices start from 45.50€.