Grosseto to Comiso trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Grosseto and arrive at Comiso every about 12 hours on average. If travelling with Trenitalia, you need to know the Grosseto to Comiso train schedule: the first train leaves at 04:19, while the last ride is at 04:19. A Grosseto to Comiso train cost about 102.55 €. But how long is the train ride from Grosseto to Comiso? Your journey takes about 19 hours on average.