Grosseto to Palermo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Grosseto and arrive at Palermo Notarbartolo every about 3 hours on average. If travelling with Trenitalia, you need to know the Grosseto to Palermo train schedule: the first train leaves at 17:30, while the last ride is at 20:29. A Grosseto to Palermo train cost about 112.35 €. But how long is the train ride from Grosseto to Palermo? Your journey takes about 16 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Grosseto to Palermo and find low cost tickets starting from 49 €!