Grosseto to Palermo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Grosseto and arrive at Palermo Notarbartolo every about 3 hours on average. If travelling with Trenitalia, you need to know the Grosseto to Palermo train schedule: the first train leaves at 17:30, while the last ride is at 20:29. A Grosseto to Palermo train cost about 112.35 €. But how long is the train ride from Grosseto to Palermo? Your journey takes about 16 hours on average.