Grottaferrata to Comiso trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Frascati and arrive at Comiso every about 4 hours on average. If travelling with Trenitalia, you need to know the Grottaferrata to Comiso train schedule: the first train leaves at 06:35, while the last ride is at 21:36. A Grottaferrata to Comiso train cost about 78.55 €. But how long is the train ride from Grottaferrata to Comiso? Your journey takes about 18 hours on average.