Grottaferrata to Niscemi trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Frascati and arrive at Niscemi every about 12 hours on average. If travelling with Trenitalia, you need to know the Grottaferrata to Niscemi train schedule: the first train leaves at 20:36, while the last ride is at 20:36. A Grottaferrata to Niscemi train cost about 89.95 €. But how long is the train ride from Grottaferrata to Niscemi? Your journey takes about 20 hours on average.