Iesi to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Jesi and arrive at Messina Centrale every about 4 hours on average. If travelling with Trenitalia, you need to know the Iesi to Messina train schedule: the first train leaves at 08:06, while the last ride is at 16:14. A Iesi to Messina train cost about 84.0 €. But how long is the train ride from Iesi to Messina? Your journey takes about 13 hours on average.