Isernia to Alcamo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Isernia and arrive at Alcamo Diramazione every about 6 hours on average. If travelling with Trenitalia, you need to know the Isernia to Alcamo train schedule: the first train leaves at 07:27, while the last ride is at 18:58. A Isernia to Alcamo train cost about 75.3 €. But how long is the train ride from Isernia to Alcamo? Your journey takes about 16 hours on average.