Isernia to Salerno trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 3 daily rides to get from Isernia to Salerno. Trains leave from Isernia and arrive at Salerno every about 4 hours on average. If travelling with Trenitalia, you need to know the Isernia to Salerno train schedule: the first train leaves at 08:25, while the last ride is at 18:58. A Isernia to Salerno train cost about 9.45 €. But how long is the train ride from Isernia to Salerno? Your journey takes about 3 hours on average.