Isernia to Trento trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Isernia and arrive at Trento every about 1 hour on average. If travelling with Trenitalia, you need to know the Isernia to Trento train schedule: the first train leaves at 07:45, while the last ride is at 20:34. A Isernia to Trento train cost about 61.4 €. But how long is the train ride from Isernia to Trento? Your journey takes about 11 hours on average.