Isernia to Velletri trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Isernia and arrive at Velletri every about 3 hours on average. If travelling with Trenitalia, you need to know the Isernia to Velletri train schedule: the first train leaves at 06:45, while the last ride is at 17:25. A Isernia to Velletri train cost about 13.8 €. But how long is the train ride from Isernia to Velletri? Your journey takes about 5 hours on average.