Isernia to Vercelli trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Isernia and arrive at Vercelli every about 6 hours on average. If travelling with Trenitalia, you need to know the Isernia to Vercelli train schedule: the first train leaves at 06:45, while the last ride is at 15:13. A Isernia to Vercelli train cost about 104.65 €. But how long is the train ride from Isernia to Vercelli? Your journey takes about 7 hours on average.