To get from Isernia a Vimodrone by train you can catch one of the 46 trains that everyday travel between Isernia and Milano Centrale, the closest station to the city. For your trip from Isernia to Milano Centrale by train you can choose to leave from one of Isernia main stations: Isernia, Roma Termini The trip by train from Isernia to Milano Centrale last on average 02:55 travelling with high-speed trains (Frecciarossa or Italotreno) If travelling with Trenitalia, you need to know the Isernia to Milano Centrale train schedule: the first train leaves at 06:00, while the last ride is at 23:00. A Isernia to Milano Centrale train cost about 34.72 €. But how long is the train ride from Isernia to Milano Centrale? Your journey takes about 4 hours on average. Trenitalia offers 36 direct trains between these two cities. Thanks to Trenitalia offers, you can save on your trip from Isernia to Milano Centrale and find prices starting from 25 €! If you need to travel this week, prices range from 49.90 € to 79.90€. Booking your train ticket a few weeks in advance though, you can find low cost trains from Isernia to Milano Centrale with fares starting from 34.72€, saving 50% on average.