La Spezia to Alessandria trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from La Spezia Centrale and arrive at Alessandria every 60 minutes on average. If travelling with Trenitalia, you need to know the La Spezia to Alessandria train schedule: the first train leaves at 04:16, while the last ride is at 17:12. A La Spezia to Alessandria train cost about 14.0 €. But how long is the train ride from La Spezia to Alessandria? Your journey takes about 3 hours on average. Trenitalia offers 4 direct trains between these two cities.