La Spezia to Cesena trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from La Spezia Centrale and arrive at Cesena every 60 minutes on average. If travelling with Trenitalia, you need to know the La Spezia to Cesena train schedule: the first train leaves at 04:43, while the last ride is at 19:04. A La Spezia to Cesena train cost about 22.25 €. But how long is the train ride from La Spezia to Cesena? Your journey takes about 5 hours on average.