La Spezia to Genoa trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from La Spezia Migliarina and arrive at Genova Piazza Principe every about 2 hours on average. If travelling with Trenitalia, you need to know the La Spezia to Genoa train schedule: the first train leaves at 06:40, while the last ride is at 21:42. A La Spezia to Genoa train cost about 8.0 €. But how long is the train ride from La Spezia to Genoa? Your journey takes about 2 hours on average. Trenitalia offers 3 direct trains between these two cities. Thanks to Trenitalia, offers, you can save on your trip from La Spezia to Genoa and find low cost tickets starting from 8 €!