Ladispoli to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Ladispoli-Cerveteri and arrive at Messina Centrale every about 2 hours on average. If travelling with Trenitalia, you need to know the Ladispoli to Messina train schedule: the first train leaves at 06:24, while the last ride is at 21:05. A Ladispoli to Messina train cost about 52.6 €. But how long is the train ride from Ladispoli to Messina? Your journey takes about 10 hours on average.