Latina to Cassino trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Sezze Romano and arrive at Cassino every 60 minutes on average. If travelling with Trenitalia, you need to know the Latina to Cassino train schedule: the first train leaves at 05:00, while the last ride is at 21:17. A Latina to Cassino train cost about 12.3 €. But how long is the train ride from Latina to Cassino? Your journey takes about 3 hours on average.