Latina to Comiso trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Latina and arrive at Comiso every about 3 hours on average. If travelling with Trenitalia, you need to know the Latina to Comiso train schedule: the first train leaves at 22:05, while the last ride is at 23:01. A Latina to Comiso train cost about 95.65 €. But how long is the train ride from Latina to Comiso? Your journey takes about 17 hours on average.