Latina to Niscemi trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Latina and arrive at Niscemi every about 12 hours on average. If travelling with Trenitalia, you need to know the Latina to Niscemi train schedule: the first train leaves at 23:01, while the last ride is at 23:01. A Latina to Niscemi train cost about 82.65 €. But how long is the train ride from Latina to Niscemi? Your journey takes about 18 hours on average.