Latina to Palermo trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 3 daily rides to get from Latina to Palermo. If travelling with Trenitalia, you need to know the Latina to Palermo train schedule: the first train leaves at 22:05, while the last ride is at 23:01. A Latina to Palermo train cost about 96.6 €. But how long is the train ride from Latina to Palermo? Your journey takes about 12 hours on average.