Lecce to Mestre trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Lecce and arrive at Salerno every 60 minutes on average. If travelling with Trenitalia, you need to know the Lecce to Mestre train schedule: the first train leaves at 07:15, while the last ride is at 16:15. A Lecce to Mestre train cost about 20.45 €. But how long is the train ride from Lecce to Mestre? Your journey takes about 7 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Lecce to Mestre and find low cost tickets starting from 20 €!