Lissone to Alpignano trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Lissone-Muggio' and arrive at Alpignano every 60 minutes on average. If travelling with Trenitalia, you need to know the Lissone to Alpignano train schedule: the first train leaves at 05:57, while the last ride is at 19:27. A Lissone to Alpignano train cost about 12.95 €. But how long is the train ride from Lissone to Alpignano? Your journey takes about 3 hours on average.