Lissone to Niscemi trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 3 daily rides to get from Lissone to Niscemi. Trains leave from Lissone-Muggio' and arrive at Niscemi every about 4 hours on average. If travelling with Trenitalia, you need to know the Lissone to Niscemi train schedule: the first train leaves at 18:12, while the last ride is at 19:42. A Lissone to Niscemi train cost about 113.05 €. But how long is the train ride from Lissone to Niscemi? Your journey takes about 9 hours on average.