Lissone to Ragusa trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Lissone-Muggio' and arrive at Ragusa every about 4 hours on average. If travelling with Trenitalia, you need to know the Lissone to Ragusa train schedule: the first train leaves at 15:57, while the last ride is at 19:12. A Lissone to Ragusa train cost about 121.95 €. But how long is the train ride from Lissone to Ragusa? Your journey takes about 13 hours on average.