Macerata to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Macerata and arrive at Messina Centrale every about 6 hours on average. If travelling with Trenitalia, you need to know the Macerata to Messina train schedule: the first train leaves at 06:23, while the last ride is at 14:47. A Macerata to Messina train cost about 90.1 €. But how long is the train ride from Macerata to Messina? Your journey takes about 14 hours on average.