Manduria to Caltanissetta trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Oria and arrive at Caltanissetta Centrale every about 12 hours on average. If travelling with Trenitalia, you need to know the Manduria to Caltanissetta train schedule: the first train leaves at 21:00, while the last ride is at 21:00. A Manduria to Caltanissetta train cost about 53.2 €. But how long is the train ride from Manduria to Caltanissetta? Your journey takes about 24 hours on average.