Manduria to Enna trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Oria and arrive at Enna every about 12 hours on average. If travelling with Trenitalia, you need to know the Manduria to Enna train schedule: the first train leaves at 21:00, while the last ride is at 21:00. A Manduria to Enna train cost about 51.55 €. But how long is the train ride from Manduria to Enna? Your journey takes about 23 hours on average.