Manduria to Syracuse trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 1 daily rides to get from Manduria to Syracuse. Trains leave from Oria and arrive at Siracusa every about 12 hours on average. If travelling with Trenitalia, you need to know the Manduria to Syracuse train schedule: the first train leaves at 08:13, while the last ride is at 08:13. A Manduria to Syracuse train cost about 69.05 €. But how long is the train ride from Manduria to Syracuse? Your journey takes about 15 hours on average.