Manfredonia to Acireale trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Manfredonia and arrive at Acireale every about 12 hours on average. If travelling with Trenitalia, you need to know the Manfredonia to Acireale train schedule: the first train leaves at 17:40, while the last ride is at 17:40. A Manfredonia to Acireale train cost about 63.9 €. But how long is the train ride from Manfredonia to Acireale? Your journey takes about 14 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Manfredonia to Acireale and find low cost tickets starting from 65 €!