Manfredonia to Ancona trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Manfredonia and arrive at Ancona every about 12 hours on average. If travelling with Trenitalia, you need to know the Manfredonia to Ancona train schedule: the first train leaves at 05:53, while the last ride is at 05:53. A Manfredonia to Ancona train cost about 37.8 €. But how long is the train ride from Manfredonia to Ancona? Your journey takes about 5 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Manfredonia to Ancona and find low cost tickets starting from 22 €!