Manfredonia to Milazzo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Manfredonia and arrive at Milazzo every about 12 hours on average. If travelling with Trenitalia, you need to know the Manfredonia to Milazzo train schedule: the first train leaves at 17:40, while the last ride is at 17:40. A Manfredonia to Milazzo train cost about 107.9 €. But how long is the train ride from Manfredonia to Milazzo? Your journey takes about 13 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Manfredonia to Milazzo and find low cost tickets starting from 64 €!