Manfredonia to Varese trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Manfredonia and arrive at Varese every about 4 hours on average. If travelling with Trenitalia, you need to know the Manfredonia to Varese train schedule: the first train leaves at 06:38, while the last ride is at 20:40. A Manfredonia to Varese train cost about 65.6 €. But how long is the train ride from Manfredonia to Varese? Your journey takes about 11 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Manfredonia to Varese and find low cost tickets starting from 48 €!