Mariano Comense to Osimo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Milano Centrale, Mariano Comense, Milano Porta Garibaldi, Firenze S. M. Novella and arrive at Ancona, Osimo-Castelfidardo every 15 minutes on average. If travelling with Trenitalia, you need to know the Mariano Comense to Osimo train schedule: the first train leaves at 06:15, while the last ride is at 21:15. A Mariano Comense to Osimo train cost about 12.90 €. But how long is the train ride from Mariano Comense to Osimo? Your journey takes about 5 hours on average. Trenitalia offers 13 direct trains between these two cities. If you need to travel this week, prices range from 40.50 € to 54.90€. Booking your train ticket a few weeks in advance though, you can find low cost trains from Mariano Comense to Osimo with fares starting from 24.90€, saving 46% on average.