Marsala to Alessandria trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Spagnuola and arrive at Napoli Centrale every about 12 hours on average. If travelling with Trenitalia, you need to know the Marsala to Alessandria train schedule: the first train leaves at 14:17, while the last ride is at 14:17. A Marsala to Alessandria train cost about 100.1 €. But how long is the train ride from Marsala to Alessandria? Your journey takes about 17 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Marsala to Alessandria and find low cost tickets starting from 69 €!