Massafra to Palermo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Massafra and arrive at Palermo Centrale every about 4 hours on average. If travelling with Trenitalia, you need to know the Massafra to Palermo train schedule: the first train leaves at 08:28, while the last ride is at 22:05. A Massafra to Palermo train cost about 42.3 €. But how long is the train ride from Massafra to Palermo? Your journey takes about 16 hours on average.