Mazara del Vallo to Frosinone trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Mazara del Vallo and arrive at Frosinone every about 3 hours on average. If travelling with Trenitalia, you need to know the Mazara del Vallo to Frosinone train schedule: the first train leaves at 06:36, while the last ride is at 16:46. A Mazara del Vallo to Frosinone train cost about 81.0 €. But how long is the train ride from Mazara del Vallo to Frosinone? Your journey takes about 20 hours on average.