Mazara del Vallo to Rome trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Mazara del Vallo and arrive at Roma Termini every about 12 hours on average. If travelling with Trenitalia, you need to know the Mazara del Vallo to Rome train schedule: the first train leaves at 16:51, while the last ride is at 16:51. A Mazara del Vallo to Rome train cost about 106.3 €. But how long is the train ride from Mazara del Vallo to Rome? Your journey takes about 17 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Mazara del Vallo to Rome and find low cost tickets starting from 69 €!