Melegnano to Noto trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Melegnano and arrive at Noto every about 3 hours on average. If travelling with Trenitalia, you need to know the Melegnano to Noto train schedule: the first train leaves at 07:38, while the last ride is at 19:08. A Melegnano to Noto train cost about 111.65 €. But how long is the train ride from Melegnano to Noto? Your journey takes about 21 hours on average.