Melzo to Caltagirone trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Melzo and arrive at Caltagirone every about 6 hours on average. If travelling with Trenitalia, you need to know the Melzo to Caltagirone train schedule: the first train leaves at 16:57, while the last ride is at 19:13. A Melzo to Caltagirone train cost about 116.0 €. But how long is the train ride from Melzo to Caltagirone? Your journey takes about 12 hours on average.