Melzo to Caltanissetta trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Melzo and arrive at Caltanissetta Centrale every about 6 hours on average. If travelling with Trenitalia, you need to know the Melzo to Caltanissetta train schedule: the first train leaves at 17:59, while the last ride is at 19:14. A Melzo to Caltanissetta train cost about 91.0 €. But how long is the train ride from Melzo to Caltanissetta? Your journey takes about 9 hours on average.