Melzo to Castelvetrano trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Melzo and arrive at Castelvetrano every about 6 hours on average. If travelling with Trenitalia, you need to know the Melzo to Castelvetrano train schedule: the first train leaves at 16:57, while the last ride is at 19:13. A Melzo to Castelvetrano train cost about 116.25 €. But how long is the train ride from Melzo to Castelvetrano? Your journey takes about 12 hours on average.