Mesagne to Caltanissetta trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Mesagne and arrive at Caltanissetta Centrale every about 12 hours on average. If travelling with Trenitalia, you need to know the Mesagne to Caltanissetta train schedule: the first train leaves at 20:35, while the last ride is at 20:35. A Mesagne to Caltanissetta train cost about 54.6 €. But how long is the train ride from Mesagne to Caltanissetta? Your journey takes 4 minutes on average.