Mesagne to Enna trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 1 daily rides to get from Mesagne to Enna. Trains leave from Mesagne and arrive at Enna every about 12 hours on average. If travelling with Trenitalia, you need to know the Mesagne to Enna train schedule: the first train leaves at 20:35, while the last ride is at 20:35. A Mesagne to Enna train cost about 52.95 €. But how long is the train ride from Mesagne to Enna? Your journey takes about 23 hours on average.