Mesagne to Niscemi trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 1 daily rides to get from Mesagne to Niscemi. The first train to Niscemi leaves from Mesagne at 08:00 and the last train departs at 08:00. If you choose a local train the trip lasts on average 00:17 hours. For your trip from Mesagne to Niscemi by train you can choose to leave from one of Mesagne main stations: Mesagne On Wanderio you can compare all schedules, fares and railway companies to Niscemi and book the best itinerary starting from Mesagne.