Mesagne to Siderno trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Mesagne and arrive at Siderno every about 6 hours on average. If travelling with Trenitalia, you need to know the Mesagne to Siderno train schedule: the first train leaves at 07:04, while the last ride is at 08:00. A Mesagne to Siderno train cost about 23.2 €. But how long is the train ride from Mesagne to Siderno? Your journey takes about 8 hours on average.