Mesagne to Venice trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 2 daily rides to get from Mesagne to Venice. Trains leave from Mesagne and arrive at Venezia S. Lucia every about 6 hours on average. If travelling with Trenitalia, you need to know the Mesagne to Venice train schedule: the first train leaves at 04:38, while the last ride is at 13:10. A Mesagne to Venice train cost about 71.6 €. But how long is the train ride from Mesagne to Venice? Your journey takes about 11 hours on average.