Messina to Ancona trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Messina Centrale and arrive at Ancona every about 3 hours on average. If travelling with Trenitalia, you need to know the Messina to Ancona train schedule: the first train leaves at 00:35, while the last ride is at 22:10. A Messina to Ancona train cost about 48.0 €. But how long is the train ride from Messina to Ancona? Your journey takes about 14 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Messina to Ancona and find low cost tickets starting from 54 €!