Messina to Ancona trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Messina Centrale and arrive at Ancona every about 3 hours on average. If travelling with Trenitalia, you need to know the Messina to Ancona train schedule: the first train leaves at 00:35, while the last ride is at 22:10. A Messina to Ancona train cost about 57.80 €. But how long is the train ride from Messina to Ancona? Your journey takes about 14 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Messina to Ancona and find low cost tickets starting from 22 €! When booking your train ticket a few weeks in advance though, you can find low cost trains from Messina to Ancona with fares starting from 47.65€, saving up to 17%.