Messina to Caltagirone trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Messina Centrale and arrive at Caltagirone every about 3 hours on average. If travelling with Trenitalia, you need to know the Messina to Caltagirone train schedule: the first train leaves at 09:38, while the last ride is at 16:35. A Messina to Caltagirone train cost about 9.7 €. But how long is the train ride from Messina to Caltagirone? Your journey takes about 5 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Messina to Caltagirone and find low cost tickets starting from 10 €!